EpiPen cost: how to pay less for epinephrine

Brand vs. generic

On August 16, 2018, the FDA approved Teva’s epinephrine injection, 0.15 mg and 0.3 mg, as the first generic of EpiPen Jr and EpiPen (FDA). The FDA says approved generics work the same way as the brand and usually cost less (FDA). If your pharmacy gives you a different device than you’re used to, ask the pharmacist to show you how to use it. MedlinePlus says training devices without medicine or a needle are available for practice (MedlinePlus).

The Illinois $60 cap

• The rule. An Illinois law says that an insurer that covers epinephrine injectors can’t make you pay more than $60 for a twin-pack, regardless of the type of injector. The cap took effect January 1, 2025 (215 ILCS 5/356z.33).
• The exception. It doesn’t apply where it would disqualify a high-deductible plan from being HSA-eligible (215 ILCS 5/356z.33).
• Kids are covered. State-regulated plans must cover medically necessary epinephrine injectors for people 18 and under (215 ILCS 5/356z.33).
• Check your plan. State insurance laws don’t reach every plan, so if you’re charged more than $60, call your plan and ask whether this Illinois law applies to it.

What about the nasal spray?

In August 2024 the FDA approved neffy, the first epinephrine for anaphylaxis that isn’t an injection. It was approved for adults and children who weigh at least 66 pounds. It’s a single-dose spray, and a second dose can be given in the same nostril with a new device if symptoms don’t improve (FDA). The FDA says nasal polyps or past nasal surgery may affect absorption (FDA). Ask your doctor whether it’s right for you and check your plan’s coverage before you switch.

Don’t let expired devices cost you

• MedlinePlus says to check the expiration date on each device and replace it when the date passes. Look at the solution from time to time, and call your doctor for a new device if it’s discolored or has particles (MedlinePlus).
• Store it in its carrying tube at room temperature, away from light, heat and moisture, and not in the bathroom (MedlinePlus). A car or a steamy bathroom can shorten its life.
• Put the expiration dates on your calendar, so you can refill before they run out and compare prices instead of paying whatever the nearest pharmacy charges.

More ways to save

• Ask your doctor for a prescription for two twin-packs if you need devices at home and at school or work, then ask your plan how it counts them.
• Compare a discount card price with your copay. See how discount cards work.
• HRSA-funded health centers offer care on a sliding fee based on income. Find one near you.
• Illinois open enrollment for 2027 plans runs November 1, 2026 to January 15, 2027 at Get Covered Illinois.
• On Medicare? Ask about Extra Help with drug costs (Medicare.gov). A discount card purchase doesn’t count toward your Part D out-of-pocket limit (Medicare.gov).

Have asthma too? See our asthma inhaler cost guide.